Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.32 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435917 | 0.96 | DDB1 (0.32) | DDB1CRBNRAMP1CALCRLSCN9A | |
| SCHEMBL8172844 | 0.96 | DDB1 (0.33) | DDB1CRBNSCN9AADRB3ADRA2B | |
| SCHEMBL13798443 | 0.95 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL13435892 | 0.95 | DDB1 (0.33) | DDB1CRBN | |
| SCHEMBL13798446 | 0.95 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13435828 | 0.95 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13798444 | 0.95 | DDB1 (0.32) | DDB1CRBN | |
| SCHEMBL13798427 | 0.94 | ADRB3 (0.32) | DDB1CRBNADRB3ADRA2BADRA2C | |
| SCHEMBL13435749 | 0.94 | DDB1 (0.32) | DDB1CRBNADRB3ADRA2BADRA2C | |
| SCHEMBL13435829 | 0.94 | DDB1 (0.32) | DDB1CRBNADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155209-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155209-A1 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, HCCS | DDB1 499/4885CRBN 1884/4885RAMP1 3386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.