Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228076 | 1.00 | ADAM17 (1.00) | ADAM17 | |
| SCHEMBL8232178 | 0.93 | ADAM17 (0.88) | ADAM17 | |
| SCHEMBL8227908 | 0.93 | ADAM17 (0.86) | ADAM17 | |
| SCHEMBL8420462 | 0.90 | ADAM17 (0.82) | ADAM17 | |
| SCHEMBL13773440 | 0.90 | ADAM17 (0.82) | ADAM17 | |
| SCHEMBL14466437 | 0.89 | ADAM17 (0.81) | ADAM17 | |
| SCHEMBL6005070 | 0.89 | ADAM17 (1.00) | ADAM17 | |
| SCHEMBL8227390 | 0.89 | ADAM17 (0.81) | ADAM17 | |
| SCHEMBL8226936 | 0.89 | ADAM17 (0.80) | ADAM17 | |
| SCHEMBL8226960 | 0.89 | ADAM17 (0.80) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687527-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |