SCHEMBL1343655

SCHEMBL1343655

Cc1cc(-c2cnccn2)[nH]n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.47
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
GFER P55789 1/20 0.40
POLB P06746 1/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 2/20 0.38
RECQL P46063 2/20 0.38
GAA P10253 1/20 0.38
NPY5R Q15761 2/20 0.37
NISCH Q9Y2I1 1/20 0.37
ADORA2A P29274 1/20 0.37
CHEK1 O14757 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP2A6 P11509 1/20 0.35
HTT P42858 1/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
ALK Q9UM73 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13815661 0.78 HSP90AA1 (0.43) PIM1ALDH1A1TDP1GFERKDM4E
SCHEMBL6080370 0.77 PIM1 (0.41) PIM1ALDH1A1TDP1GFERPOLB
SCHEMBL15926104 0.74 CCR1 (0.57) PIM1ALDH1A1KDM4ENPSR1CYP2A6
SCHEMBL2623420 0.74 KDM4E (0.46) PIM1TDP1POLBKDM4ECYP1A2
SCHEMBL18674806 0.74 PIM1 (0.38) PIM1ALDH1A1TDP1GFERPOLB
SCHEMBL15500839 0.73 CDC7 (0.39) ADORA2A
SCHEMBL31601664 0.73 MKNK1 (0.41) PIM1NISCHCHEK1PIM3PIM2
SCHEMBL17280002 0.73 ALDH1A1 (0.58) PIM1ALDH1A1POLBCYP3A4CYP1A2
SCHEMBL15374805 0.72 SMN1; SMN2 (0.37) ALDH1A1POLBKDM4ECYP3A4CYP1A2
SCHEMBL6580330 0.72 PIM1 (0.57) PIM1ALDH1A1TDP1GFERPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed