SCHEMBL13436701

SCHEMBL13436701

C[C@H]1CN(c2nc3cc(-c4ccc5c(ccn5C)c4)ccc3o2)C[C@@H](Cl)O1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478320 0.93 FAAH (1.00) FAAH
SCHEMBL3478026 0.93 FAAH (1.00) FAAH
SCHEMBL3477995 0.83 FAAH (0.78) FAAH
SCHEMBL3477463 0.82 FAAH (0.77) FAAH
SCHEMBL3475426 0.81 FAAH (0.75) FAAH
SCHEMBL3476620 0.80 FAAH (1.00) FAAH
SCHEMBL3476334 0.80 FAAH (0.95) FAAH
SCHEMBL3476187 0.79 FAAH (0.98) FAAH
SCHEMBL3475629 0.79 FAAH (0.98) FAAH
SCHEMBL3477228 0.79 FAAH (0.84) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed