Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 5/20 | 0.73 |
| ▸ | MTOR | P42345 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 14/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13403517 | 0.88 | PRKDC (0.78) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13403506 | 0.87 | PRKDC (0.77) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL4109272 | 0.85 | PRKDC (1.00) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL13403505 | 0.84 | PRKDC (0.72) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL4111209 | 0.80 | PRKDC (0.66) | PRKDCPIK3CDPIK3CBPIK3CA | |
| SCHEMBL4110120 | 0.80 | PRKDC (0.65) | PRKDC | |
| SCHEMBL3717836 | 0.78 | PRKDC (0.81) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL3717834 | 0.78 | PRKDC (0.81) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL3716359 | 0.76 | PRKDC (0.79) | PRKDCMTORPIK3CDPIK3CBPIK3CA | |
| SCHEMBL3718346 | 0.74 | PRKDC (0.73) | PRKDCMTORPIK3CDPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696203-B2 | DNA-PK inhibitors | KUDOS PHARMACEUTICALS LIMITED (GB) | 2010-04-13 | — | — | US | disclosed |