SCHEMBL1343883

SCHEMBL1343883

N#CC(CC(=O)O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.51
GABBR2 O75899 1/20 0.48
GABBR1 Q9UBS5 1/20 0.48
TSHR P16473 1/20 0.47
KMT2A Q03164 1/20 0.44
CYP2C19 P33261 1/20 0.44
EEF2K O00418 1/20 0.43
TRPA1 O75762 1/20 0.42
CPA1 P15085 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9556420 1.00 FFAR1 (0.51) FFAR1GABBR2GABBR1TSHRKMT2A
SCHEMBL27862777 1.00 FFAR1 (0.51) FFAR1GABBR2GABBR1TSHRKMT2A
SCHEMBL1754734 0.85 TSHR (0.53) TSHRKMT2ACYP2C19TRPA1
SCHEMBL434696 0.85 ESR1 (0.58) FFAR1KMT2ACYP2C19
SCHEMBL6798718 0.85 CYP2C19 (0.47) GABBR2GABBR1TSHRKMT2ACYP2C19
SCHEMBL31326025 0.85 TSHR (0.53) TSHRKMT2ACYP2C19TRPA1
SCHEMBL6063192 0.85 CYP2C19 (0.47) GABBR2GABBR1TSHRKMT2ACYP2C19
SCHEMBL3055864 0.85 TSHR (0.44) FFAR1GABBR2GABBR1TSHRKMT2A
SCHEMBL11568787 0.85 KMT2A (0.46) FFAR1GABBR2GABBR1TSHRKMT2A
SCHEMBL10260682 0.83 FFAR1 (0.62) FFAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117110481-A Auxiliary determination method for unknown ketone-containing perfume in tobacco essence 吉林烟草工业有限责任公司 2023-11-24 CN claimed
CN-117074574-A Method for assisting in determining unknown aldehyde-containing perfume in tobacco essence 吉林烟草工业有限责任公司 2023-11-17 CN claimed
CN-119776295-A Olefin reductase, coding gene, vector, engineering bacteria and application thereof 浙江工业大学 2025-04-08 CN disclosed
CN-118530130-A Preparation method of henibut 杭州国瑞生物科技有限公司 2024-08-23 CN disclosed
CN-117110481-A Auxiliary determination method for unknown ketone-containing perfume in tobacco essence 吉林烟草工业有限责任公司 2023-11-24 CN disclosed
CN-117088744-A Method for constructing fluorine-containing compound by catalyzing decarboxylation of alkyl carboxylic acid by ketone compound 中山大学 2023-11-21 CN disclosed
CN-117074574-A Method for assisting in determining unknown aldehyde-containing perfume in tobacco essence 吉林烟草工业有限责任公司 2023-11-17 CN disclosed
US-20210380548-A1 Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family CTXT PTY LIMITED (AU) 2021-12-09 US disclosed
EP-3676266-A1 FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY Ctxt Pty Ltd (AU) 2020-07-08 EP disclosed
WO-2019043139-A1 FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY CTXT PTY LIMITED (AU) 2019-03-07 WO disclosed
CN-107188808-A A kind of synthetic method of the phenylbutyric acid hydrochloride of 4 amino 3 江苏斯威森生物医药工程研究中心有限公司 2017-09-22 CN disclosed
US-5366987-A Enzyme inhibitors, anticholesterol WARNER-LAMBERT COMPANY (US) 1994-11-22 US disclosed
WO-1994019330-A1 HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS WARNER-LAMBERT COMPANY (US) 1994-09-01 WO disclosed
EP-0600950-A1 AMIDE TETRAZOLE ACAT INHIBITORS. WARNER LAMBERT CO (US) 1994-06-15 EP disclosed
US-5242939-A Hypotensive WARNER-LAMBERT COMPANY (US) 1993-09-07 US disclosed
WO-1993004052-A1 AMIDE TETRAZOLE ACAT INHIBITORS WARNER-LAMBERT COMPANY (US) 1993-03-04 WO disclosed
EP-0219961-B1 IRREVERSIBLE DOPAMINE-B-HYDROXYLASE INHIBITORS SMITHKLINE BECKMAN CORPORATION (US) 1989-03-08 EP disclosed
US-4760089-A Benzonitrile derivative; enzyme inhibitor SMITHKLINE BECKMAN CORPORATION (US) 1988-07-26 US disclosed
EP-0219961-A1 Irreversible dopamine-B-hydroxylase inhibitors SMITHKLINE BECKMAN CORPORATION (US) 1987-04-29 EP disclosed
US-4153713-A NEUROPSYCHOTROPIC AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380548-A1 Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family KAT5, KAT6A, KAT2A FFAR1 4034/4885GABBR2 3937/4885GABBR1 3990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.