Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | HTR1F | P30939 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439478 | 0.77 | KDM4E (0.41) | CYP1A2PTK2KDM4ELMNAMAPK8 | |
| SCHEMBL8340280 | 0.75 | KDM4E (0.51) | CYP1A2KDM4ELMNAMAPK8L3MBTL1 | |
| SCHEMBL5632488 | 0.74 | CYP1A2 (0.53) | CYP1A2PTK2KDM4ELMNAMAPK8 | |
| SCHEMBL13439484 | 0.73 | CYP1A2 (0.50) | CYP1A2KDM4ELMNAMAPK8ADORA2B | |
| SCHEMBL30311946 | 0.73 | CYP1A2 (0.51) | CYP1A2PTK2KDM4ELMNAMAPK8 | |
| SCHEMBL16685587 | 0.73 | KDM4E (0.46) | CYP1A2PTK2KDM4ELMNAMAPK8 | |
| SCHEMBL10200326 | 0.73 | KDM4E (0.46) | CYP1A2PTK2KDM4ELMNAMAPK8 | |
| SCHEMBL29013232 | 0.73 | CYP1A2 (0.51) | CYP1A2PTK2KDM4ELMNAMAPK8 | |
| SCHEMBL23714119 | 0.72 | KDM4E (0.50) | PTK2KDM4ELMNAMAPK8HSP90AA1 | |
| SCHEMBL28405620 | 0.72 | KDM4E (0.46) | PTK2KDM4ELMNAMAPK8HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7692011-B2 | 8-hydroxy and 8-mercapto quinazolinones | PRANA BIOTECHNOLOGY LIMITED (AU) | 2010-04-06 | — | — | US | disclosed |