Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439478 | 0.82 | KDM4E (0.41) | CYP1A2ADORA3MAPK8KDM4ELMNA | |
| SCHEMBL13313408 | 0.73 | CCR1 (0.43) | CYP1A2ALDH1A1HTTKDM4E | |
| SCHEMBL11543102 | 0.73 | ADORA3 (0.48) | CYP1A2ADORA3SMN1; SMN2MAPK8ALDH1A1 | |
| SCHEMBL13439477 | 0.73 | CYP1A2 (0.43) | CYP1A2ADORA3MAPK8KDM4ELMNA | |
| SCHEMBL11548951 | 0.72 | ADORA3 (0.44) | CYP1A2ADORA3SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL19126696 | 0.70 | MAPK8 (0.69) | CYP1A2ADORA3MAPK8KDM4ELMNA | |
| SCHEMBL19127704 | 0.70 | CYP1A2 (0.50) | CYP1A2ADORA3SMN1; SMN2MAPK8LMNA | |
| SCHEMBL30675590 | 0.69 | MAPK8 (0.48) | CYP1A2ADORA3MAPK8ALDH1A1KDM4E | |
| SCHEMBL15305693 | 0.69 | CYP1A2 (0.80) | CYP1A2ADORA3SMN1; SMN2MAPK8ALDH1A1 | |
| SCHEMBL16942775 | 0.69 | DYRK1A (0.56) | CYP1A2ADORA3SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7692011-B2 | 8-hydroxy and 8-mercapto quinazolinones | PRANA BIOTECHNOLOGY LIMITED (AU) | 2010-04-06 | — | — | US | disclosed |