SCHEMBL1344100

SCHEMBL1344100

c1ccc(CCN(CCc2ccccc2)CCc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 5/20 0.65
TAAR1 Q96RJ0 1/20 0.64
AOC3 Q16853 2/20 0.58
OPRM1 P35372 5/20 0.57
OPRD1 P41143 4/20 0.57
TDP1 Q9NUW8 1/20 0.57
DRD3 P35462 2/20 0.55
DRD2 P14416 1/20 0.55
CHRM2 P08172 1/20 0.54
HTR1A P08908 1/20 0.54
ADRA2A P08913 1/20 0.54
CHRM1 P11229 1/20 0.54
DRD1 P21728 1/20 0.54
SLC6A2 P23975 1/20 0.54
SLC6A4 P31645 1/20 0.54
ADRA1A P35348 1/20 0.54
SLC6A3 Q01959 1/20 0.54
KCNH2 Q12809 1/20 0.54
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12049808 0.97 OPRK1 (0.63) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL13658167 0.90 OPRK1 (0.57) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL9768688 0.88 TAAR1 (0.58) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL552965 0.88 DRD3 (0.71) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL6567560 0.88 OPRK1 (0.60) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL4269278 0.88 OPRK1 (0.55) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL13937396 0.88 TAAR1 (0.58) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL11875312 0.88 OPRK1 (0.55) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL14047033 0.87 OPRK1 (0.69) OPRK1TAAR1AOC3OPRM1OPRD1
SCHEMBL231061 0.87 OPRK1 (0.63) OPRK1TAAR1AOC3OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138669-B1 PROCESS FOR THE PREPARATION OF SILANES FROM METHYLDICHLOROSILANE AND CHLOROSILANES RHONE-POULENC CHIMIE (FR) 1988-08-10 EP claimed
EP-0138670-B1 PROCESS FOR THE PREPARATION OF SILANES WITH A SI-H BOND BY REDISTRIBUTION RHONE-POULENC CHIMIE (FR) 1988-05-25 EP claimed
US-4746752-A QUATERNARY OR TERTIARY AMINE CATALYST RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-24 US claimed
EP-0105382-B1 IMAGE-FORMING PHOTO-SENSITIVE MATERIAL SONY CORPORATION (JP) 1987-01-07 EP claimed
US-4605543-A DISTRIBUTION AND DISPROPORTIONATION CATALYSIS RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1986-08-12 US claimed
EP-0138669-A2 Process for the preparation of silanes from methyldichlorosilane and chlorosilanes RHONE-POULENC CHIMIE (FR) 1985-04-24 EP claimed
EP-0138670-A2 Process for the preparation of silanes with a Si-H bond by redistribution RHONE-POULENC CHIMIE (FR) 1985-04-24 EP claimed
US-4069242-A SYNERGISTIC CATALYST SYSTEM CONTAINING AMMONIUM OR AMINE NITROGEN AND IRON OR CHROMIUM COMPOUND THE DOW CHEMICAL COMPANY (US) 1978-01-17 US claimed
US-11987772-B2 Solvent composition CENTRAL GLASS COMPANY, LIMITED (JP) 2024-05-21 US disclosed
US-20210238507-A1 SOLVENT COMPOSITION CENTRAL GLASS COMPANY, LIMITED (JP) 2021-08-05 US disclosed
EP-3831918-A1 SOLVENT COMPOSITION Central Glass Company, Limited (JP) 2021-06-09 EP disclosed
US-9969950-B2 Lubricating oil compositions containing sterically hindered amines as ashless TBN sourcces INFINEUM INTERNATIONAL LIMITED (GB) 2018-05-15 US disclosed
US-9969950-B2 Lubricating oil compositions containing sterically hindered amines as ashless TBN sourcces INFINEUM INTERNATIONAL LIMITED (GB) 2018-05-15 US disclosed
US-9969950-B2 Lubricating oil compositions containing sterically hindered amines as ashless TBN sourcces INFINEUM INTERNATIONAL LIMITED (GB) 2018-05-15 US disclosed
US-4035321-A Preparation of ultraviolet curable acrylated polymers CELANESE CORPORATION (US) 1977-07-12 US disclosed
US-4016334-A Method of applying high adhesion ultraviolet curable coatings and coated articles CELANESE CORPORATION (US) 1977-04-05 US disclosed
US-4008293-A ACRYLIC COPOLYMER, AMINOPLAST, BINDER PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
US-3992276-A Unsaturated polyesters for ultraviolet curable coatings CELANESE CORPORATION (US) 1976-11-16 US disclosed
US-3992275-A Low gloss ultraviolet curable coatings utilizing α,α,α-trichlorotoluene as a photoinitiator CELANESE CORPORATION (US) 1976-11-16 US disclosed
US-3984397-A CYCLIZATION FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-10-05 US disclosed