Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18470544 | 0.91 | MAPT (0.49) | KMT2ARXFP1MAPTCYP19A1THRB | |
| SCHEMBL6489298 | 0.91 | KMT2A (0.46) | KMT2ARXFP1MAPTCYP19A1THRB | |
| SCHEMBL11686956 | 0.91 | KMT2A (0.46) | KMT2ARXFP1MAPTCYP19A1THRB | |
| SCHEMBL11662919 | 0.91 | KMT2A (0.68) | KMT2ARXFP1MAPTCYP19A1THRB | |
| SCHEMBL18470539 | 0.87 | KMT2A (0.42) | KMT2ARXFP1MAPTCYP19A1THRB | |
| SCHEMBL22005143 | 0.83 | ACLY (0.48) | KMT2ARXFP1MAPTCYP19A1THRB | |
| SCHEMBL6478331 | 0.82 | MAPT (0.62) | RXFP1MAPTTHRBADORA2BLMNA | |
| SCHEMBL3686929 | 0.81 | KMT2A (0.76) | KMT2ARXFP1MAPTCYP19A1APP | |
| SCHEMBL18470558 | 0.80 | KMT2A (0.46) | KMT2ARXFP1MAPTCYP19A1MAOA | |
| SCHEMBL7947787 | 0.79 | CYP2A6 (0.49) | KMT2AMAPTCYP19A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100073602-A1 | INDOLE COMPOUND-CONTAINING COMPOSITION AND LIGHT-EMITTING DEVICE USING THE COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-25 | — | — | US | disclosed |