Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344416 | 0.92 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1345077 | 0.89 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1344773 | 0.87 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL6940988 | 0.87 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1344751 | 0.83 | CYP3A4 (0.49) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1344101 | 0.83 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1749863 | 0.83 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1344219 | 0.82 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1345044 | 0.81 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 | |
| SCHEMBL1345043 | 0.81 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19LMNACYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114904-B1 | ANTIFUNGAL TRIAZOLE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAE WOONG PHARMA (KR) | 2013-08-21 | — | — | EP | claimed |
| US-8063229-B2 | Antifungal triazole derivatives, method for the preparation thereof and pharmaceutical composition containing same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2011-11-22 | — | — | US | claimed |
| US-20100063285-A1 | ANTIFUNGAL TRIAZOLE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-03-11 | — | — | US | claimed |
| EP-2114904-B1 | ANTIFUNGAL TRIAZOLE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAE WOONG PHARMA (KR) | 2013-08-21 | — | — | EP | disclosed |
| US-8063229-B2 | Antifungal triazole derivatives, method for the preparation thereof and pharmaceutical composition containing same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2011-11-22 | — | — | US | disclosed |
| US-20100063285-A1 | ANTIFUNGAL TRIAZOLE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063285-A1 | ANTIFUNGAL TRIAZOLE DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CYP51A1, ERG28, CYP3A5 | CYP3A4 7/4885CYP2C9 8/4885CYP2C19 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.