Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 5/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365649 | 0.89 | HINT1 (0.45) | HINT1PNPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL5216686 | 0.78 | HINT1 (0.46) | HINT1PNPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL21184283 | 0.78 | TYMP (0.36) | TAS1R3TAS1R1HPGD | |
| SCHEMBL18759035 | 0.78 | TYMP (0.36) | TAS1R3TAS1R1HPGD | |
| SCHEMBL21171618 | 0.78 | TYMP (0.36) | TAS1R3TAS1R1HPGD | |
| SCHEMBL18759043 | 0.78 | TYMP (0.36) | TAS1R3TAS1R1HPGD | |
| SCHEMBL18769139 | 0.78 | TYMP (0.36) | TAS1R3TAS1R1HPGD | |
| SCHEMBL21163079 | 0.78 | TYMP (0.36) | TAS1R3TAS1R1HPGD | |
| SCHEMBL25688968 | 0.77 | KDM4E (0.44) | HINT1TAS1R3TAS1R1HPGDSTING1 | |
| SCHEMBL12991055 | 0.77 | HINT1 (0.33) | HINT1TAS1R3TAS1R1HPGDSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2540734-A2 | Process and reagents for oligonucleotide synthesis and purification | Alnylam Pharmaceuticals, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| US-8063198-B2 | Processes and reagents for desilylation of oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-11-22 | — | — | US | disclosed |