SCHEMBL1344485

SCHEMBL1344485

N#Cc1ccc2cc(C#N)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.54
IMPDH2 P12268 1/20 0.54
IMPDH1 P20839 1/20 0.54
CYP11B1 P15538 2/20 0.52
CYP11B2 P19099 2/20 0.52
CYP17A1 P05093 1/20 0.52
CA2 P00918 3/20 0.50
CA1 P00915 2/20 0.50
SLC6A2 P23975 5/20 0.47
SLC6A4 P31645 5/20 0.47
SLC6A3 Q01959 3/20 0.47
F2 P00734 1/20 0.47
PLG P00747 1/20 0.47
PLAU P00749 1/20 0.47
KLKB1 P03952 1/20 0.47
PRSS1 P07477 1/20 0.47
ALDH1A1 P00352 1/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489119 1.00 CYP2A6 (0.54) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL13074509 0.94 CYP2A6 (0.50) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL29489123 0.91 CYP2A6 (0.52) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL1341822 0.91 CYP2A6 (0.52) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL60579 0.89 CA1 (0.59) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
Water SCHEMBL1898776 0.89 CA1 (0.59) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL31150958 0.89 CA1 (0.59) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL2761110 0.87 CA1 (0.57) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL16875675 0.87 CA1 (0.57) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL5778680 0.87 IMPDH2 (0.45) CYP2A6IMPDH2IMPDH1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843953-A Crystalline covalent triazine polymer material and preparation method and application thereof 中国科学院兰州化学物理研究所 2024-04-09 CN claimed
CN-116239759-A Conjugated two-dimensional polymer film and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-06-09 CN claimed
CN-114790286-A Preparation method of covalent triazine framework polymer microspheres 绍兴文理学院 2022-07-26 CN claimed
CN-113912844-B Triazine ring connection-based aromatic two-dimensional organic framework nano material and preparation method thereof 中国矿业大学 2022-06-21 CN claimed
CN-113912844-A Triazine ring connection-based aromatic two-dimensional organic framework nano material and preparation method thereof 中国矿业大学 2022-01-11 CN claimed
CN-110841619-B Method for preparing porous oxide by carbon template method 沈阳建筑大学 2021-05-25 CN claimed
CN-109244388-B Preparation and application of covalent organic framework/titanium carbide nanosheet composite material 同济大学 2021-05-11 CN claimed
CN-110841619-A Method for preparing porous oxide by carbon template method 沈阳建筑大学 2020-02-28 CN claimed
CN-109244388-A Covalent organic framework/titanium carbide nanosheet composite material preparation and application 同济大学 2019-01-18 CN claimed
US-4104279-A Process for N-aroylimides SUNTECH, INC. (US) 1978-08-01 US claimed
US-4034005-A REACTIVE DISTILLATION OF AROMATIC NITRILE EQUILIBRIUM HYDROLYSIS MIXTURE SUN VENTURES, INC. (US) 1977-07-05 US claimed
US-4013705-A ALKALI METAL VANADIUM BRONZE CATALYST PROMOTED BY IRON SUNTECH, INC. (US) 1977-03-22 US claimed
US-3987078-A FROM 2,6-DIMETHYLNAPHTHALENE, ALKALI METAL-VANADIUM-BRONZE CATALYST SUNTECH, INC. (US) 1976-10-19 US claimed
CN-114196204-B Prepreg, laminate, metal foil-clad laminate, printed wiring board, and multilayer printed wiring board 三菱瓦斯化学株式会社 2024-07-16 CN disclosed
CN-118251445-A Cyclic organosiloxane containing imide bond and polymerizable unsaturated bond and curable resin composition containing the same 信越化学工业株式会社 2024-06-25 CN disclosed
CN-118251457-A Thermosetting resin composition, prepreg and printed wiring board 三菱瓦斯化学株式会社 2024-06-25 CN disclosed
US-3985805-A Preparation of alkylcarboxamides SUN VENTURES, INC. (US) 1976-10-12 US disclosed
US-3965160-A OXIDATION SUN VENTURES, INC. (US) 1976-06-22 US disclosed
US-3887605-A Process for recovery of 2,6-dicyanonaphthalene SUN VENTURES INC 1975-06-03 US disclosed
US-3887605-A Process for recovery of 2,6-dicyanonaphthalene SUN VENTURES INC 1975-06-03 US disclosed