Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830876 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL19864905 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL2077166 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL18432213 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL19864899 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL19852529 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL18097955 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL60470 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL21707988 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| Ammonia Solution, Strong SCHEMBL20236062 | 0.98 | HPGD (0.69) | HPGDSMN1; SMN2USP2EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4530 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260048071-A1 | 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS | Cadrenal Therapeutics, Inc. | 2026-02-19 | — | — | US | claimed |
| US-20260027123-A1 | Compositions for Modulating Lipoxygenase and Methods of Using Same | UNIV CALIFORNIA (US) | 2026-01-29 | — | — | US | claimed |
| EP-4615432-A2 | 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS | Veralox Therapeutics Inc. (US) | 2025-09-17 | — | — | EP | claimed |
| EP-4612135-A1 | ORAL PHARMACEUTICAL FORMULATIONS CONTAINING 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES | Veralox Therapeutics Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| EP-4558508-A1 | COMPOSITIONS FOR MODULATING LIPOXYGENASE AND METHODS OF USING SAME | The Regents of the University of California (US) | 2025-05-28 | — | — | EP | claimed |
| CN-116478143-B | Donepezil derivative, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2025-05-09 | — | — | CN | claimed |
| CN-119899173-A | Preparation method of ceritinib as toxic impurity nitrosoceritinib of ceritinib gene | 南京亿华药业有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-117229205-B | Preparation method and pharmaceutical application of phenyl acrylamide RHbDD1 inhibitor | 中国医学科学院基础医学研究所 | 2025-03-21 | — | — | CN | claimed |
| CN-119490451-A | Compounds as positive modulators of calcium activated chloride channels | TMEM16A有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-113924146-B | Novel compounds and pharmaceutical compositions thereof for the treatment of diseases | 加拉帕戈斯股份有限公司 | 2024-12-10 | — | — | CN | claimed |
| EP-1434782-A2 | 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF | University of Virginia Patent Foundation (US) | 2004-07-07 | — | — | EP | claimed |
| EP-0935465-B1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2004-04-14 | — | — | EP | claimed |
| US-20030186926-A1 | 2-propynyl adenosine analogs having A2A agonist activity and compositions thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-10-02 | — | — | US | claimed |
| WO-2003080125-A2 | BENZIMIDAZOLES AND THEIR USE AS MITOGEN-ACTIVATED- AND RHO-KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | claimed |
| WO-2003045950-A1 | PYRAZOLOPYRIDINE DERIVTIVES AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | claimed |
| CN-1420881-A | Beta-amino acid derivs. as inhibitors of matrix metalloproteases and TNF-alpha | BRISTOL MYERS SQUIBB PHARMACEU (US) | 2003-05-28 | — | — | CN | claimed |
| WO-2003029264-A2 | 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2003-04-10 | — | — | WO | claimed |
| US-20020198252-A1 | Process for the preparation of alkylamine substituted indoles | PAYACK JOSEPH (US) | 2002-12-26 | — | — | US | claimed |
| US-6214844-B1 | ANTIARTHRITIC AGENTS; BONE DISORDERS; ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2001-04-10 | — | — | US | claimed |
| US-5977103-A | Substituted imidazole compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | claimed |