Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13445 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL3830876 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL19864905 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL2077166 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL18432213 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL19864899 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL19852529 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL18097955 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| SCHEMBL60470 | 1.00 | HPGD (0.71) | HPGDSMN1; SMN2USP2EPHX1MEN1 | |
| Ammonia Solution, Strong SCHEMBL20236062 | 0.98 | HPGD (0.69) | HPGDSMN1; SMN2USP2EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048194-A1 | SUBSTITUTED BENZAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048194-A1 | SUBSTITUTED BENZAMIDES | TAAR1, TAAR5, NPY1R | HPGD 4397/4885SMN1; SMN2 1965/4885USP2 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.