SCHEMBL1344696

SCHEMBL1344696

CCC(C)(C)c1ccc(O)c(C(C)c2cc(C(C)(C)CC)cc(C(C)c3cc(C(C)(C)CC)ccc3O)c2O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.51
MAPK1 P28482 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
ESR1 P03372 8/20 0.39
ESR2 Q92731 5/20 0.39
AR P10275 3/20 0.39
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345195 1.00 RORC (0.51) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL1345305 1.00 RORC (0.51) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL1344878 1.00 RORC (0.51) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL1345533 1.00 RORC (0.51) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL51093 0.94 RORC (0.57) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL12435286 0.83 RORC (0.57) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL11876501 0.82 RORC (0.75) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL28336750 0.82 RORC (0.49) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL12424214 0.81 RORC (0.54) RORCMAPK1SMN1; SMN2NPC1LMNA
SCHEMBL12424225 0.81 RORC (0.36) RORCMAPK1SMN1; SMN2NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1724119-B1 DEVELOPER MIXTURE FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS MITSUBISHI CHEM CORP (JP) 2014-11-19 EP disclosed
US-8062993-B2 Developer mixture for thermal recording materials and thermal recording materials API CORPORATION (JP) 2011-11-22 US disclosed
CN-1930006-B Developer mixture for thermal recording materials and thermal recording materials API CORP 2010-12-08 CN disclosed
US-20070173407-A1 Developer mixture for thermal recording materials and thermal recording materials API CORPORATION (JP) 2007-07-26 US disclosed
CN-1930006-A Developer mixture for thermal recording materials and thermal recording materials API CORP (JP) 2007-03-14 CN disclosed
EP-1724119-A1 DEVELOPER MIXTURE FOR THERMAL RECORDING MATERIALS AND THERMAL RECORDING MATERIALS API Corporation (JP) 2006-11-22 EP disclosed