Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072587 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL14389921 | 0.80 | DRD2 (0.42) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL13169444 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL8261456 | 0.80 | DRD2 (0.47) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL13095146 | 0.77 | GFER (0.39) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL8529136 | 0.76 | DRD2 (0.42) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL13244147 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL10289629 | 0.76 | AR (0.51) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL12829063 | 0.74 | GFER (0.39) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL8527546 | 0.73 | DRD2 (0.41) | SMN1; SMN2ALDH1A1MAPTDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025436-A2 | NITROGEN AND SULFUR-CONTAINING HETEROCYCLE DERIVATIVES | TRIAD MULTITECH PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | WO | disclosed |