Phenprobamate

Phenprobamate

SCHEMBL134496

NC(=O)OCCCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
SMN1; SMN2 Q16637 3/20 0.60
NPC1 O15118 1/20 0.60
RECQL P46063 1/20 0.60
RAB9A P51151 1/20 0.60
IDO1 P14902 1/20 0.57
ALDH1A1 P00352 2/20 0.54
TDP1 Q9NUW8 1/20 0.53
HDAC3 O15379 1/20 0.52
MAPK1 P28482 1/20 0.52
ADRA1A P35348 1/20 0.52
HDAC4 P56524 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC11 Q96DB2 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenprobamate SCHEMBL27286516 0.98 LMNA (0.96) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1835165 0.94 LMNA (0.89) LMNASMN1; SMN2NPC1RECQLRAB9A
Phenprobamate SCHEMBL28192759 0.93 LMNA (0.87) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1837161 0.93 LMNA (0.86) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1840540 0.93 LMNA (0.86) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1838456 0.93 LMNA (0.86) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1838924 0.93 LMNA (0.86) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1833113 0.93 LMNA (0.86) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL11306452 0.93 LMNA (0.86) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL26773863 0.90 LMNA (0.81) LMNASMN1; SMN2NPC1RECQLRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11003 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025062440-A1 TOPICAL NANO-DISPERSION COMPOSITIONS AND THEIR PREPARATION THEREOF PULSE PHARMACEUTICALS PVT. LTD (IN) 2025-03-27 WO claimed
US-20240307386-A1 NOVEL METHODS INTRA-CELLULAR THERAPIES, INC. 2024-09-19 US claimed
US-11945733-B2 Method for treating a fluid by upflow through a bed of adsorbent media VEOLIA WATER SOLUTIONS & TECHNOLOGIES SUPPORT (FR) 2024-04-02 US claimed
US-20240076206-A1 Method for Treating Water by Adsorption on Activated Carbon Coupled with an Addition of Ozone, and Facility for Implementing Said Method VEOLIA WATER SOLUTIONS & TECHNOLOGIES SUPPORT (FR) 2024-03-07 US claimed
US-20230381168-A1 ADJUNCTIVE THERAPY FOR DEPRESSION ANEUROTECH BV (BE) 2023-11-30 US claimed
US-11787712-B2 Water treatment plant having integrated ballasted flocculation and decantation, and a corresponding method VEOLIA WATER SOLUTIONS & TECHNOLOGIES SUPPORT (FR) 2023-10-17 US claimed
EP-3797092-B1 METHOD FOR TREATING A FLUID BY UPFLOW THROUGH A BED OF ADSORBENT MEDIA VEOLIA WATER SOLUTIONS & TECH (FR) 2023-08-30 EP claimed
EP-3648863-B1 WATER TREATMENT PLANT HAVING INTEGRATED BALLASTED FLOCCULATION AND DECANTATION, AND A CORRESPONDING METHOD VEOLIA WATER SOLUTIONS & TECH (FR) 2023-08-16 EP claimed
CN-113234183-B Clathrate monomer based on subject-object recognition, preparation method thereof, starch-styrene-acrylic antibacterial emulsion, and preparation method and application thereof 西北民族大学 2022-07-22 CN claimed
US-11390868-B2 Treatment of filaggrin (FLG) related diseases by modulation of FLG expression and activity CURNA, INC. (US) 2022-07-19 US claimed
US-4844873-A Separation and recovery of solids from liquids containing them using the ionic flotation process INSTITUT NATIONAL DE RECHERCHE CHIMIQUE APPLIQUE (FR) 1989-07-04 US claimed
CN-1033257-A double-sided printing device and method VIAUD REMI (FR) 1989-06-07 CN claimed
CN-1032838-A The operating method of gas turbine group ASEA STAL AB (SE) 1989-05-10 CN claimed
CN-1030198-A The preparation technology of dibrominated iodine compound anion resin and its intermediate iodine bromide IBr SHANGHAI YIKANG MINERAL WATER (CN) 1989-01-11 CN claimed
CN-1030012-A MULTI-FUNCTIONAL SUPPORT STAND FOR DOMESTIC DECORATION YANG LIEFANG (CN) 1989-01-04 CN claimed
US-4726715-A Screw powder feeders QUANTUM LASER CORPORATION (US) 1988-02-23 US claimed
CN-85109112-A Kamalan type hovercraft 1986-09-03 CN claimed
WO-1986002337-A1 SCREW POWDER FEEDERS QUANTUM LASER (UK) LIMITED (GB) 1986-04-24 WO claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed
US-4120680-A HIGH PRESSURE DROP ACROSS A POROUS MEMBRANE PILKINGTON BROTHERS LIMITED (GB) 1978-10-17 US claimed