Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102836 | 0.83 | CNR1 (0.44) | CYP3A4CYP2C9SLC9A1CYP2C19SMYD3 | |
| SCHEMBL13779954 | 0.82 | KDM4E (0.44) | CYP3A4CYP2C9SLC9A1CYP2C19SMYD3 | |
| SCHEMBL29944596 | 0.82 | CNR1 (0.47) | CYP3A4CYP2C9SLC9A1CYP2C19SMYD3 | |
| SCHEMBL14731465 | 0.81 | SMYD3 (0.46) | APOBEC3AAPOBEC3GCYP3A4CYP2C9SLC9A1 | |
| SCHEMBL3214224 | 0.79 | CYP3A4 (0.43) | CYP3A4CYP2C9SLC9A1CYP2C19SMYD3 | |
| SCHEMBL3214218 | 0.79 | CYP3A4 (0.45) | CYP3A4CYP2C9SLC9A1CYP2C19SMYD3 | |
| SCHEMBL14085105 | 0.79 | SIGMAR1 (0.44) | CYP3A4CYP2C9SLC9A1CYP2C19SMYD3 | |
| SCHEMBL12645325 | 0.77 | RECQL (0.49) | HPGDALDH1A1TP53SMN1; SMN2CA12 | |
| SCHEMBL12233312 | 0.77 | GLRA1 (0.46) | CYP3A4CYP2C9SLC9A1CYP2C19SMYD3 | |
| SCHEMBL15004007 | 0.76 | CNR2 (0.49) | SMYD3HPGDCNR2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773796-B1 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-03-03 | — | — | EP | disclosed |