Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118560 | 0.89 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4HRH1MCHR1 | |
| SCHEMBL25740887 | 0.89 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4HRH1MCHR1 | |
| SCHEMBL1931211 | 0.88 | HRH1 (0.59) | SLC6A2SLC6A3SLC6A4HRH1MCHR1 | |
| SCHEMBL14654961 | 0.88 | HRH1 (0.59) | SLC6A2SLC6A3SLC6A4HRH1MCHR1 | |
| SCHEMBL19641737 | 0.85 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4HRH1CARM1 | |
| SCHEMBL18610915 | 0.85 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4HRH1CARM1 | |
| SCHEMBL18610907 | 0.85 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4HRH1CARM1 | |
| SCHEMBL15627269 | 0.80 | SLC6A4 (0.60) | SLC6A2SLC6A3SLC6A4MCHR1 | |
| SCHEMBL29856 | 0.80 | HRH1 (0.71) | SLC6A2SLC6A3SLC6A4HRH1CARM1 | |
| Ammonia Solution, Strong SCHEMBL8078606 | 0.78 | HRH1 (0.68) | SLC6A2SLC6A3SLC6A4HRH1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751113-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-03-10 | — | — | EP | disclosed |