Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118560 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4HRH1MCHR1 | |
| SCHEMBL13450146 | 0.89 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4HRH1MCHR1 | |
| SCHEMBL15448447 | 0.84 | FURIN (0.46) | MCHR1FURINFFAR4RAB9A | |
| SCHEMBL18610915 | 0.82 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4HRH1CHRNB4 | |
| SCHEMBL18610907 | 0.82 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4HRH1CHRNB4 | |
| SCHEMBL19641737 | 0.82 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4HRH1CHRNB4 | |
| SCHEMBL796490 | 0.82 | HRH1 (0.65) | SLC6A2SLC6A3SLC6A4HRH1FURIN | |
| SCHEMBL29502908 | 0.82 | MCHR1 (0.51) | SLC6A2SLC6A3SLC6A4MCHR1FURIN | |
| Ammonia Solution, Strong SCHEMBL8081694 | 0.80 | HRH1 (0.63) | SLC6A2SLC6A3SLC6A4HRH1FURIN | |
| Fluoride SCHEMBL28194548 | 0.80 | HRH1 (0.63) | SLC6A2SLC6A3SLC6A4HRH1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122581-A2 | IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |