⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14816929 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL21845035 | 0.82 | TSHR (0.32) | — | |
| SCHEMBL14213401 | 0.78 | GRIK1 (0.31) | — | |
| SCHEMBL13971291 | 0.78 | GRIK1 (0.31) | — | |
| SCHEMBL18923945 | 0.78 | — | — | |
| SCHEMBL23029593 | 0.76 | — | — | |
| SCHEMBL13786730 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL17928532 | 0.76 | — | — | |
| SCHEMBL11965884 | 0.76 | — | — | |
| SCHEMBL20646726 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10668090-B2 | Liver specific delivery-based antiviral prodrug nucleoside cyclophosphate compound and uses thereof | ZHEJIANG PALO ALTO PHARMACEUTICALS, INC (CN) | 2020-06-02 | — | — | US | disclosed |
| US-20190125771-A1 | LIVER SPECIFIC DELIVERY-BASED ANTIVIRAL PRODRUG NUCLEOSIDE CYCLOPHOSPHATE COMPOUND AND USES THEREOF | ZHEJIANG PALO ALTO PHARMACEUTICALS,INC (CN) | 2019-05-02 | — | — | US | disclosed |
| US-20190100792-A1 | PROBE FOR SELECTIVELY CHARACTERIZING ENZYMES INVOLVED IN XENOBIOTIC METABOLISM AND METHOD OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE | 2019-04-04 | — | — | US | disclosed |
| EP-3272747-A1 | METHOD OF PREPARATION FOR LEDIPASVIR AND DERIVATIVE THEREOF, AND INTERMEDIATE COMPOUND FOR PREPARATION OF LEDIPASVIR | Shanghai Forefront Pharmceutical Co., Ltd (CN) | 2018-01-24 | — | — | EP | disclosed |
| EP-2513711-B1 | METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS | NOVARTIS AG (CH) | 2017-07-12 | — | — | EP | disclosed |
| US-9604910-B2 | Composition of 5-nitrobenzoate derivatives as anti-metastatic agent that inhibits tumor cell-induced platelet aggregation | CHANG GUNG UNIVERSITY (TW) | 2017-03-28 | — | — | US | disclosed |
| WO-2013012848-A1 | BENZAMIDES | MERCK PATENT GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |
| EP-1389110-B1 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | AVANIR PHARMACEUTICALS (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-1105413-B1 | HEPATITIS C INHIBITOR TRI-PEPTIDES | BOEHRINGER INGELHEIM CA LTD (CA) | 2009-04-29 | — | — | EP | disclosed |