Ecenofloxacin

Ecenofloxacin

SCHEMBL1345141

C[C@@]12C[C@H](N)[C@@H]1CN(c1nc3c(cc1F)c(=O)c(C(=O)O)cn3C1CC1)C2

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.63
CHRM2 P08172 2/20 0.56
DRD1 P21728 1/20 0.56
LMNA P02545 3/20 0.52
KDM4E B2RXH2 2/20 0.52
HSD17B10 Q99714 2/20 0.52
ABCC4 O15439 1/20 0.52
KMT2A Q03164 1/20 0.47
DHFR P00374 1/20 0.46
EPHA2 P29317 1/20 0.46
FLT4 P35916 1/20 0.46
GSK3B P49841 1/20 0.46
RARB P10826 1/20 0.46
TBXAS1 P24557 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ALDH1A1 P00352 2/20 0.44
POLB P06746 2/20 0.44
HPGD P15428 1/20 0.44
XBP1 P17861 1/20 0.44
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ecenofloxacin SCHEMBL5415313 1.00 DPP4 (0.63) DPP4CHRM2DRD1LMNAKDM4E
Ecenofloxacin SCHEMBL12590150 1.00 DPP4 (0.63) DPP4CHRM2DRD1LMNAKDM4E
Ecenofloxacin SCHEMBL5415321 1.00 DPP4 (0.63) DPP4CHRM2DRD1LMNAKDM4E
Ecenofloxacin SCHEMBL8863108 1.00 DPP4 (0.63) DPP4CHRM2DRD1LMNAKDM4E
Ecenofloxacin SCHEMBL9066847 1.00 DPP4 (0.63) DPP4CHRM2DRD1LMNAKDM4E
Ecenofloxacin SCHEMBL7841221 1.00 DPP4 (0.63) DPP4CHRM2DRD1LMNAKDM4E
Ecenofloxacin SCHEMBL1230672 0.99 DPP4 (0.62) DPP4CHRM2DRD1LMNAKDM4E
SCHEMBL16518637 0.93 DPP4 (0.54) DPP4CHRM2DRD1LMNAKDM4E
SCHEMBL7849063 0.92 DPP4 (0.62) DPP4CHRM2DRD1LMNAKDM4E
SCHEMBL9067081 0.92 DPP4 (0.62) DPP4CHRM2DRD1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226084-A9 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS TECHFIELDS PHARMA CO., LTD. (CN) 2024-07-11 US claimed
US-20240131017-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS TECHFIELDS PHARMA CO., LTD. (CN) 2024-04-25 US claimed
US-20240115562-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS TECHFIELDS PHARMA CO., LTD. (CN) 2024-04-11 US claimed
US-20230285572-A1 TARGETED DELIVERY OF THERAPEUTIC AGENTS SEPELO THERAPEUTICS, LLC 2023-09-14 US claimed
US-11679118-B2 Parasite therapy BORODY THOMAS J (AU) 2023-06-20 US claimed
EP-4188433-A2 TARGETED DELIVERY OF THERAPEUTIC AGENTS Sepelo Therapeutics, LLC (US) 2023-06-07 EP claimed
WO-2023028364-A1 TARGETED COMPOSITIONS AND USES THEROF SEPELO THERAPEUTICS, LLC (US) 2023-03-02 WO claimed
US-20220184101-A1 PARASITE THERAPY BORODY THOMAS J (AU) 2022-06-16 US claimed
WO-2022031761-A2 TARGETED DELIVERY OF THERAPEUTIC AGENTS SEPELO THERAPEUTICS, LLC (US) 2022-02-10 WO claimed
US-20160045490-A1 USE OF CHEMOTHERAPEUTIC AGENTS BAYER INNOVATION GMBH (DE) 2016-02-18 US claimed
US-20070197501-A1 Use Of Chemotherapeutic Agents BAYER INNOVATION GMBH (DE) 2007-08-23 US claimed
EP-1408034-B1 Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents SCHULZ & SCHLIMBACH GBR (DE) 2007-08-08 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
CN-1668598-A Use of chemotherapeutic agents SCHULZ & SCHLIMBACH GBR (DE) 2005-09-14 CN claimed
EP-1408034-A1 Use of Quinoline derivatives as antibacterial agents Schulz & Schlimbach GbR (DE) 2004-04-14 EP claimed
US-20030045544-A1 Bactericides for the oral region of animals using 3-carboxy-4-oxo quinoline or 1,8-naphthyridine derivatives or 1-cyclopropyl-3-carboyx-4-oxo quinolizine derivatives BAYER INNOVATION GMBH (DE) 2003-03-06 US claimed
EP-1244434-A2 USE OF CHEMOTHERAPEUTIC AGENTS Schulz, Hans-Herrmann (DE) 2002-10-02 EP claimed
EP-0677050-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES CHEIL JEDANG CORP (KR) 2001-08-16 EP claimed
WO-2001045679-A2 USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT SCHULZ HANS HERRMANN (DE) 2001-06-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226084-A9 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS HRH4, HCAR2, PAH DPP4 940/4885CHRM2 618/4885DRD1 4330/4885
US-20030045544-A1 Bactericides for the oral region of animals using 3-carboxy-4-oxo quinoline or 1,8-naphthyridine derivatives or 1-cyclopropyl-3-carboyx-4-oxo quinolizine derivatives NQO2, BROX, CYP4X1 DPP4 307/4885CHRM2 3393/4885DRD1 265/4885
US-20240115562-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS HRH4, HCAR2, PAH DPP4 940/4885CHRM2 618/4885DRD1 4330/4885
US-20070197501-A1 Use Of Chemotherapeutic Agents TYMP, TP53, MSH2 DPP4 2790/4885CHRM2 4725/4885DRD1 3984/4885
US-20240131017-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS HRH4, HCAR2, PAH DPP4 940/4885CHRM2 618/4885DRD1 4330/4885
US-20160045490-A1 USE OF CHEMOTHERAPEUTIC AGENTS TYMP, TP53, MSH2 DPP4 2790/4885CHRM2 4725/4885DRD1 3984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.