BROX

BRO1 domain-containing protein BROX · Q5VW32 · BROX on Sugi Atlas →

0 patent compounds predicted against BROX, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to BROX by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Trial With Broccoli Sprout Extract to Patients With Type 2 Diabetes PHASE2COMPLETED
FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer PHASE2COMPLETED
Sulforaphane Treatment of Children With Autism Spectrum Disorder (ASD) PHASE1/PHASE2COMPLETED
Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB) PHASE1/PHASE2RECRUITING
A Study of BL-B01D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors PHASE1RECRUITING
Broccoli Sprout Extract in Treating Patients With Breast Cancer EARLY_PHASE1COMPLETED
A Window of Opportunity Study of Black Raspberry for Patients With HNSCC EARLY_PHASE1WITHDRAWN
Genes Contributing to Hereditary Ovarian Cancer in Women and BRCA1/2 Wildtype Families nanCOMPLETED
Broccoli Sulforaphane Bioavailability With Mustard nanCOMPLETED
Green Vegetables and Women's Health nanCOMPLETED
The Effects of Broccoli Sprout Extract on Obstructive Lung Disease nanCOMPLETED
Broccoli Sprout Extract in Preventing Lung Cancer in Smokers nanCOMPLETED
The Effect of Broccoli Sprouts as a Nutritional Supplement in the Prevention of Cardiovascular Disease nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate Cancer nanCOMPLETED
Effects of Sulforaphane (SFN) on Immune Response to Live Attenuated Influenza Virus in Smokers and Nonsmokers nanCOMPLETED
Broccoli Sprout Extract for Cognitive Function nanRECRUITING
BSCU1 and Immune Function nanCOMPLETED
Effect of Broccoli Sprout Extract in Patients With Chronic Kidney Disease With Diabetes Type 2 nanCOMPLETED
Daily Consumption of Well-Cooked Broccoli May Affect Glucosinolate Metabolites and Inflammatory Biomarkers nanCOMPLETED
Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation nanCOMPLETED
Sulphate Accumulation in Prostate nanCOMPLETED
Broccoli, Peas and PIN nanCOMPLETED
Effects of 2 Different Broccoli Sprout Containing Supplements on Nasal Cells in Healthy Volunteers nanCOMPLETED
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Amyotrophic Lateral Sclerosis (ALS) Tissue Donation Program nanCOMPLETED
Wheat Germ Supplementation Will Improve Markers of Gut Health, Inflammation, and Insulin Resistance in Overweight Adults nanCOMPLETED
Effects of the Consumption of Broccoli Sprouts in Overweight Subjects nanCOMPLETED
Study of the Effect of Innate on the Inflammatory Response to Endotoxin nanRECRUITING
Expression of TET1 Gene in Acute Leukaemia nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a BROX binder may also engage these)

ProteinNameSimilarity
Q5RDD7 1.000 Q5RDD7 →
A3KQV2 0.997 A3KQV2 →
Q4V8K5 0.996 Q4V8K5 →
Q8K2Q7 0.996 Q8K2Q7 →
A4IIL4 0.994 A4IIL4 →
SRP68 Signal recognition particle subunit SRP68 0.974 landscape →
Q8BMA6 0.969 Q8BMA6 →
Q00004 0.969 Q00004 →
Q6P1I3 0.968 Q6P1I3 →
P48553 0.967 P48553 →
Q6IR80 0.967 Q6IR80 →
Q96MD2 0.964 Q96MD2 →
GTF3C3 General transcription factor 3C polypeptide 3 0.960 landscape →
Q96ES7 0.960 Q96ES7 →
A2AT37 0.960 A2AT37 →
Q1L8F9 0.960 Q1L8F9 →
Q8N960 0.959 Q8N960 →
Q62245 0.959 Q62245 →
P97878 0.959 P97878 →
Q9TS33 0.959 Q9TS33 →
API5 Apoptosis inhibitor 5 0.958 landscape →
SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0.958 landscape →
Q9DA08 0.958 Q9DA08 →
P97891 0.958 P97891 →
Q8BHL5 0.957 Q8BHL5 →
Q6P4T2 0.957 Q6P4T2 →
Q9H9A5 0.957 Q9H9A5 →
Q56A27 0.957 Q56A27 →
A2AGL3 0.957 A2AGL3 →
Q5ZMW3 0.956 Q5ZMW3 →