Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.42 |
| ▸ | DRD2 | P14416 | 13/20 | 0.42 |
| ▸ | HTR7 | P34969 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 9/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.37 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.37 |
| ▸ | RPS17 | P08708 | 1/20 | 0.37 |
| ▸ | RPSA | P08865 | 1/20 | 0.37 |
| ▸ | RPS2 | P15880 | 1/20 | 0.37 |
| ▸ | RPL35A | P18077 | 1/20 | 0.37 |
| ▸ | RPL7 | P18124 | 1/20 | 0.37 |
| ▸ | RPL17 | P18621 | 1/20 | 0.37 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.37 |
| ▸ | RPS3 | P23396 | 1/20 | 0.37 |
| ▸ | RPS12 | P25398 | 1/20 | 0.37 |
| ▸ | RPL13 | P26373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734245 | 0.87 | HTR2A (0.43) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL13453339 | 0.85 | HTR2A (0.49) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL2733202 | 0.84 | HTR2C (0.51) | HTR2ADRD2HTR7HTR6 | |
| SCHEMBL20404164 | 0.80 | MEN1 (0.49) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL2734240 | 0.75 | HTR2C (0.53) | HTR2ADRD2 | |
| SCHEMBL14748264 | 0.74 | HTR2A (0.50) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL14735704 | 0.73 | HTR2A (0.51) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL14748221 | 0.73 | HTR2A (0.51) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL13013927 | 0.73 | HTR2A (0.51) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL6219432 | 0.72 | HTR2C (0.44) | HTR6HTR1AKCNH2RPLP1RPLP0 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877390-B1 | BENZISOXAZOLE PIPERAZINE COMPOUNDS AND METHODS OF USE THEREOF | HYPNION INC (US) | 2010-03-24 | — | — | EP | disclosed |