SCHEMBL1345609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1982631	0.93	ADRB2 (0.42)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL1345260	0.90	ADRB2 (0.44)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL9248857	0.88	STAT3 (0.50)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL7520230	0.87	ADRB2 (0.46)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL1344887	0.86	ADRB2 (0.41)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL1344925	0.86	STAT3 (0.46)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL1345019	0.85	GSK3B (0.50)	ADRB2STAT3GSK3BTOP2ATOP2B
	SCHEMBL9688340	0.85	ADRB2 (0.45)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL1343207	0.82	GSK3B (0.44)	ADRB2STAT3HTTGSK3BTSHR
	SCHEMBL1345069	0.82	ADRB2 (0.42)	ADRB2STAT3HTTGSK3BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.