Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 8/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27394004 | 0.79 | PGR (0.32) | PGRNR3C1ARAKR1B1 | |
| SCHEMBL7922402 | 0.78 | CREBBP (0.39) | MAOBKDM4EGAAHSD17B10BRD4 | |
| SCHEMBL21707063 | 0.77 | P2RY6 (0.33) | BRD4CREBBP | |
| SCHEMBL20708104 | 0.77 | PGR (0.40) | PGRNR3C1ARAKR1B1KDM4E | |
| SCHEMBL30991547 | 0.73 | AKR1B1 (0.39) | PGRNR3C1ARAKR1B1BRD4 | |
| SCHEMBL9035064 | 0.73 | AR (0.43) | PGRNR3C1ARAKR1B1 | |
| SCHEMBL4827151 | 0.73 | AKR1B1 (0.39) | PGRNR3C1ARAKR1B1BRD4 | |
| SCHEMBL27590550 | 0.73 | MAOB (0.33) | PGRMAOBKDM4E | |
| SCHEMBL21880533 | 0.72 | MAOB (0.43) | PGRMAOB | |
| SCHEMBL23722589 | 0.71 | PARP1 (0.50) | KDM4EGAABRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331551-B1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | EVOTEC INTERNAT GMBH (DE) | 2016-06-29 | — | — | EP | disclosed |
| WO-2010023181-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-04 | — | — | WO | disclosed |