Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457094 | 0.88 | ROCK2 (0.78) | ROCK2 | |
| SCHEMBL3238683 | 0.86 | ROCK2 (0.75) | ROCK2 | |
| SCHEMBL13457520 | 0.83 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL13457476 | 0.83 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL13457106 | 0.83 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL13457194 | 0.82 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL13457026 | 0.82 | ROCK2 (0.69) | ROCK2 | |
| SCHEMBL13457197 | 0.81 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL13457198 | 0.81 | ROCK2 (0.67) | ROCK2 | |
| SCHEMBL3261857 | 0.81 | ROCK2 (0.71) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |