Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 15/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457248 | 0.90 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL3262426 | 0.89 | ROCK2 (0.71) | ROCK2 | |
| SCHEMBL13457402 | 0.85 | ROCK2 (0.72) | ROCK2TNIK | |
| SCHEMBL3264748 | 0.84 | ROCK2 (0.76) | ROCK2 | |
| SCHEMBL13456989 | 0.84 | ROCK2 (0.75) | ROCK2 | |
| SCHEMBL3232068 | 0.84 | ROCK2 (0.68) | ROCK2 | |
| SCHEMBL13457394 | 0.84 | ROCK2 (0.78) | ROCK2 | |
| SCHEMBL3232097 | 0.80 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL13457181 | 0.79 | ROCK2 (0.64) | ROCK2 | |
| SCHEMBL13457009 | 0.77 | ROCK2 (0.66) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |