Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 1.00 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457409 | 0.89 | ROCK2 (0.80) | ROCK2AKT1MAPK8MAPK10 | |
| SCHEMBL13457391 | 0.89 | ROCK2 (1.00) | ROCK2AKT1MAPK8MAPK10 | |
| SCHEMBL3228103 | 0.88 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL13457338 | 0.87 | ROCK2 (0.77) | ROCK2 | |
| SCHEMBL3232097 | 0.86 | ROCK2 (1.00) | ROCK2AKT1MAPK8MAPK10 | |
| SCHEMBL13457406 | 0.85 | ROCK2 (0.84) | ROCK2AKT1MAPK8MAPK10 | |
| SCHEMBL3264920 | 0.84 | ROCK2 (1.00) | ROCK2AKT1MAPK8MAPK10 | |
| SCHEMBL3264335 | 0.83 | ROCK2 (0.83) | ROCK2AKT1MAPK8MAPK10 | |
| SCHEMBL13457343 | 0.82 | ROCK2 (0.78) | ROCK2 | |
| SCHEMBL13457413 | 0.81 | ROCK2 (0.76) | ROCK2AKT1MAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024903-A1 | BENZO[d]OXAZOLES AND BENZO[d]THIAZOLES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-03-04 | — | — | WO | disclosed |