Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337480 | 0.87 | ANO1 (0.45) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL1919590 | 0.87 | MEN1 (0.44) | MEN1KMT2APRNPGAAPTGS2 | |
| SCHEMBL3539094 | 0.86 | MEN1 (0.55) | MEN1KMT2APRNPGAAPTGS2 | |
| SCHEMBL1918707 | 0.85 | CYP3A4 (0.44) | — | |
| SCHEMBL3535680 | 0.83 | KDM4E (0.51) | MEN1KMT2APRNPGAAPTGS2 | |
| SCHEMBL2299438 | 0.83 | PTGS2 (0.49) | MEN1KMT2APRNPGAAPTGS2 | |
| SCHEMBL6120010 | 0.83 | MEN1 (0.55) | MEN1KMT2APRNPGAAPTGS2 | |
| SCHEMBL4790731 | 0.82 | MAPT (0.41) | MEN1KMT2APRNPGAAPTGS2 | |
| SCHEMBL12293636 | 0.82 | MEN1 (0.60) | MEN1KMT2APRNPGAAPTGS2 | |
| SCHEMBL4792280 | 0.81 | KDM4E (0.40) | MEN1KMT2APRNPGAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030592-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-03-18 | — | — | WO | disclosed |