Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711061 | 0.84 | KMT2A (0.41) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL17221080 | 0.81 | KMT2A (0.39) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL17221079 | 0.81 | KMT2A (0.39) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL1711066 | 0.80 | GPR119 (0.37) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL15817586 | 0.80 | GPR119 (0.39) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL16525745 | 0.79 | MEN1 (0.41) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL13458326 | 0.77 | MEN1 (0.40) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL20633041 | 0.77 | MEN1 (0.37) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL9975865 | 0.76 | KRAS (0.36) | KRASNR1I2KCNH2GRM2GPR119 | |
| SCHEMBL4439245 | 0.75 | MEN1 (0.42) | MEN1KMT2AALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026124-A1 | PICOLINAMIDE DERIVATIVES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2010-03-11 | — | — | WO | disclosed |