Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319252 | 0.79 | KDM4E (0.46) | — | |
| SCHEMBL30601029 | 0.79 | KDM4E (0.46) | — | |
| SCHEMBL16505348 | 0.73 | PIM1 (0.41) | — | |
| SCHEMBL31228792 | 0.73 | PIM1 (0.41) | — | |
| SCHEMBL15595551 | 0.73 | CYP1A2 (0.34) | — | |
| SCHEMBL29790224 | 0.69 | MAPT (0.45) | — | |
| SCHEMBL318417 | 0.69 | MAPT (0.45) | — | |
| SCHEMBL21989449 | 0.69 | PTPN1 (0.44) | — | |
| SCHEMBL15595568 | 0.68 | CYP1A2 (0.40) | — | |
| SCHEMBL29480787 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344474-B1 | PICOLINAMIDE DERIVATIVES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-09-23 | — | — | EP | disclosed |
| WO-2013175388-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2013-11-28 | — | — | WO | disclosed |
| WO-2010026124-A1 | PICOLINAMIDE DERIVATIVES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2010-03-11 | — | — | WO | disclosed |