Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16505348 | 1.00 | PIM1 (0.41) | PIM1DGAT1PTPN1GRM2KMT2A | |
| SCHEMBL30601029 | 0.82 | KDM4E (0.46) | KMT2ALMNA | |
| SCHEMBL319252 | 0.82 | KDM4E (0.46) | KMT2ALMNA | |
| SCHEMBL13362749 | 0.78 | PIM1 (0.50) | PIM1PTPN1GRM2KMT2ALMNA | |
| SCHEMBL16751982 | 0.76 | APP (0.42) | PIM1DGAT1PTPN1GRM2KMT2A | |
| SCHEMBL31507586 | 0.76 | PIM1 (0.41) | PIM1DGAT1PTPN1GRM2KMT2A | |
| SCHEMBL29502454 | 0.76 | TGFBR1 (0.42) | PIM1GRM2KMT2ALMNAAPP | |
| SCHEMBL26684509 | 0.76 | PIM1 (0.41) | PIM1DGAT1PTPN1GRM2KMT2A | |
| SCHEMBL2827339 | 0.76 | TGFBR1 (0.42) | PIM1GRM2KMT2ALMNAAPP | |
| SCHEMBL11347729 | 0.76 | KMT2A (0.39) | PIM1PTPN1GRM2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |