Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457996 | 1.00 | EPHX2 (0.54) | EPHX2SMYD3KMT2AXIAPLMNA | |
| SCHEMBL22987448 | 0.92 | — | — | |
| SCHEMBL3562819 | 0.92 | — | — | |
| SCHEMBL2156256 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL22979117 | 0.90 | SMYD3 (0.47) | EPHX2SMYD3KMT2AXIAPLMNA | |
| Hydrochloric Acid SCHEMBL22979118 | 0.90 | SMYD3 (0.47) | EPHX2SMYD3KMT2AXIAPLMNA | |
| SCHEMBL17690660 | 0.85 | EPHX2 (0.50) | EPHX2SMYD3KMT2AXIAPLMNA | |
| SCHEMBL17690658 | 0.85 | EPHX2 (0.50) | EPHX2SMYD3KMT2AXIAPLMNA | |
| SCHEMBL22629584 | 0.84 | EPHX1 (0.50) | SMYD3KMT2AXIAPLMNABLM | |
| SCHEMBL15906216 | 0.84 | EPHX1 (0.50) | SMYD3KMT2AXIAPLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025482-A1 | ORGANIC COMPOUNDS | NABRIVA THERAPEUTICS AG (AT) | 2010-03-11 | — | — | WO | disclosed |