Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 5/20 | 0.39 |
| ▸ | ARG2 | P78540 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17690660 | 1.00 | EPHX2 (0.50) | EPHX2SMYD3XIAPARG1ARG2 | |
| SCHEMBL15054947 | 0.92 | SMYD3 (0.46) | SMYD3XIAPARG1ARG2DPP4 | |
| SCHEMBL28661580 | 0.92 | SMYD3 (0.46) | SMYD3XIAPARG1ARG2DPP4 | |
| SCHEMBL5967831 | 0.92 | SMYD3 (0.46) | SMYD3XIAPARG1ARG2DPP4 | |
| SCHEMBL2735524 | 0.85 | KMT2A (0.48) | SMYD3XIAPARG1ARG2DPP4 | |
| SCHEMBL14655011 | 0.85 | KMT2A (0.48) | SMYD3XIAPARG1ARG2DPP4 | |
| SCHEMBL25069101 | 0.85 | EPHX1 (0.43) | EPHX2SMYD3ARG1ARG2DPP4 | |
| SCHEMBL1953167 | 0.85 | EPHX1 (0.47) | EPHX2DPP4FAPDPP8DPP9 | |
| SCHEMBL12824263 | 0.85 | EPHX1 (0.47) | EPHX2DPP4FAPDPP8DPP9 | |
| SCHEMBL1953168 | 0.85 | EPHX1 (0.47) | EPHX2DPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321272-B1 | ORGANIC COMPOUNDS | NABRIVA THERAPEUTICS AG (AT) | 2016-04-20 | — | — | EP | disclosed |