Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.69 |
| ▸ | SLC9A3 | P48764 | 18/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.68 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.53 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12363356 | 0.91 | TRPC6 (0.70) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL12363375 | 0.91 | TRPC6 (0.70) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL12363385 | 0.85 | TRPC6 (0.61) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL2414556 | 0.84 | TRPC6 (0.76) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL2414559 | 0.84 | TRPC6 (0.76) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL2408358 | 0.84 | TRPC6 (0.76) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL2408361 | 0.84 | TRPC6 (0.76) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL2260914 | 0.84 | SLC9A3 (0.77) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL2188791 | 0.84 | SLC9A3 (0.77) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 | |
| SCHEMBL2188784 | 0.84 | SLC9A3 (0.77) | TRPC6SLC9A3CYP2D6TRPC3TRPC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025856-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI-AVENTIS (FR) | 2010-03-11 | — | — | WO | disclosed |