Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14136763 | 0.94 | PSMB5 (0.42) | PSMB5HSD11B1CNR2LTB4R2RARB | |
| SCHEMBL1345833 | 0.94 | HSD11B1 (0.48) | PSMB5HSD11B1CNR2LTB4R2RARB | |
| SCHEMBL14136762 | 0.90 | HSD11B1 (0.45) | PSMB5HSD11B1CNR2LTB4R2RARB | |
| SCHEMBL6545270 | 0.87 | KDM4E (0.36) | PSMB5CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17360011 | 0.84 | HPRT1 (0.40) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13519493 | 0.83 | HSD11B1 (0.42) | PSMB5HSD11B1LTB4R2RARBBCHE | |
| SCHEMBL9236703 | 0.83 | CNR2 (0.46) | HSD11B1CNR2BCHENPC1TP53 | |
| SCHEMBL12831536 | 0.83 | CNR2 (0.55) | HSD11B1CNR2BCHEMEN1KMT2A | |
| SCHEMBL10042897 | 0.83 | CNR2 (0.55) | HSD11B1CNR2BCHEMEN1KMT2A | |
| SCHEMBL13197732 | 0.83 | CNR2 (0.55) | HSD11B1CNR2BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8062817-B2 | Crosslinked resin mixture backing layer containing photoconductor | XEROX CORPORATION (US) | 2011-11-22 | — | — | US | disclosed |