Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.54 |
| ▸ | USP2 | O75604 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28483564 | 0.79 | NPY5R (0.66) | KDM4ECLK4ALDH1A1TP53MEN1 | |
| SCHEMBL12736488 | 0.78 | LMNA (0.61) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14606852 | 0.78 | BCHE (0.68) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19933276 | 0.78 | KDM4E (0.59) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1622223 | 0.77 | CYP1A2 (0.61) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4532312 | 0.77 | APP (0.67) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12322126 | 0.77 | CYP1A2 (0.61) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12261733 | 0.77 | KDM4E (0.59) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1084165 | 0.76 | CYP1A2 (0.70) | KDM4ELMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31649377 | 0.74 | KDM4E (0.56) | KDM4ELMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030027-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-03-18 | — | — | WO | disclosed |