Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711705 | 0.84 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL4439245 | 0.77 | MEN1 (0.42) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL1711668 | 0.76 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL27191787 | 0.75 | GPBAR1 (0.43) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL15770800 | 0.75 | HTR2C (0.41) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL1711669 | 0.73 | MEN1 (0.41) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL13458086 | 0.73 | MEN1 (0.41) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL15770868 | 0.73 | SLC6A4 (0.47) | POLB | |
| SCHEMBL1711061 | 0.73 | KMT2A (0.41) | KMT2AMEN1ALDH1A1HTTRAB9A | |
| SCHEMBL1711463 | 0.70 | KMT2A (0.41) | KMT2AMEN1ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026124-A1 | PICOLINAMIDE DERIVATIVES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2010-03-11 | — | — | WO | disclosed |