Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 5/20 | 0.59 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931070 | 0.98 | TOP1 (0.60) | TOP1KIF11LTB4RMETAP2CYP2C9 | |
| SCHEMBL13458749 | 0.90 | TOP1 (0.48) | TOP1KIF11METAP2DGAT1KCNH2 | |
| SCHEMBL3358457 | 0.87 | ACACA (0.50) | TOP1MAPTKDM4ESMN1; SMN2ACACA | |
| SCHEMBL17899330 | 0.87 | ACACA (0.50) | TOP1MAPTKDM4ESMN1; SMN2ACACA | |
| SCHEMBL1745982 | 0.87 | ACACA (0.50) | TOP1MAPTKDM4ESMN1; SMN2ACACA | |
| SCHEMBL3698074 | 0.87 | ACACA (0.50) | TOP1MAPTKDM4ESMN1; SMN2ACACA | |
| SCHEMBL3358750 | 0.87 | ACACA (0.50) | TOP1MAPTKDM4ESMN1; SMN2ACACA | |
| SCHEMBL14553726 | 0.85 | TOP1 (0.50) | TOP1KIF11CYP2C9TSPOP2RY14 | |
| SCHEMBL12112655 | 0.85 | ACACA (0.51) | TOP1MAPTKDM4ESMN1; SMN2ACACA | |
| SCHEMBL5931163 | 0.85 | TOP1 (0.49) | TOP1METAP2MAOBKCNH2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |