Benzylacetone

Benzylacetone

SCHEMBL1346

CC(=O)CCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
KEAP1 Q14145 1/20 0.67
FFAR1 O14842 2/20 0.61
HDAC2 Q92769 2/20 0.57
HDAC8 Q9BY41 2/20 0.57
HDAC6 Q9UBN7 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
HDAC1 Q13547 2/20 0.56
HDAC3 O15379 1/20 0.56
MAPK1 P28482 1/20 0.56
ADRA1A P35348 1/20 0.56
HDAC4 P56524 1/20 0.56
SLC6A3 Q01959 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
KMT2A Q03164 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylacetone SCHEMBL27300714 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL27633494 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL27945817 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL29892054 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL29808345 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL23581088 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL10786223 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL11768872 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL21048732 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL27421035 0.98 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13182 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076371-A1 AGROCHEMICAL COMPOSITION OF TRIAZOLES ADAMA MAKHTESHIM LTD. (IL) 2026-03-19 US claimed
EP-4711010-A2 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2026-03-18 EP claimed
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
US-20260028562-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION DANSTAR FERMENT AG (CH) 2026-01-29 US claimed
US-20260028600-A1 TRANSAMINASE POLYPEPTIDES CODEXIS INC (US) 2026-01-29 US claimed
US-20260026501-A1 AGROCHEMICAL COMPOSITION OF SDHI FUNGICIDES ADAMA MAKHTESHIM LTD. (IL) 2026-01-29 US claimed
US-20250369024-A1 Acyloin Condensation Reactions, Enzymes, and Products Thereof MOJIA BIOTECH PTE LTD (SG) 2025-12-04 US claimed
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
US-12448611-B2 Transaminase polypeptides CODEXIS, INC. (US) 2025-10-21 US claimed
US-12421475-B2 High performing, high impact bloom accord with a top, medium, and base note mixture INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US claimed
EP-0092787-B1 PROCESS FOR THE PREPARATION OF A PHENYLALKYLAMINOETHYLSALICYLAMIDE SCHERING CORPORATION (US) 1986-08-27 EP claimed
US-4533742-A USING RHODIUM CARBONYL CATALYST TEXACO INC. (US) 1985-08-06 US claimed
US-4493904-A COORDINATION, POLYMERIZATION CATALYST CONTAINING TITANIUM TRICHORI CONOCO INC. (US) 1985-01-15 US claimed
US-4422908-A SULFAMATE, BORIC ACID, SODIUM OR POTASSIUM CHLORIDE, ALKALI CARBOXYLATE, AROMATIC CARBONYL COMPOUND, SULFONATED OIL, POLYETHER SURFACTANT E. I. DU PONT DE NEMOURS & CO. (US) 1983-12-27 US claimed
EP-0092787-A1 Process for the preparation of a phenylalkylaminoethylsalicylamide SCHERING CORPORATION (US) 1983-11-02 EP claimed
US-4151309-A FOODS, CHEWING GUM, DENTIFRICES, DRUGS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-04-24 US claimed
US-4136208-A FLAVORING WITH SUBSTITUTED NORBORNANE DERIVATIVES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-01-23 US claimed
US-4076853-A Flavoring with substituted norbornane derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-02-28 US claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-4000327-A BERRY FRUIT FOODSTUFFS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-12-28 US claimed