Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460146 | 0.82 | MAPT (0.54) | MAPTALDH1A1LMNAPDK2NAMPT | |
| SCHEMBL1919801 | 0.81 | ALDH1A1 (0.60) | MAPTALDH1A1LMNAPDK2CKS1B | |
| SCHEMBL20231640 | 0.80 | SUV39H2 (0.49) | MAPTALDH1A1LMNAPDK2CKS1B | |
| SCHEMBL30952688 | 0.80 | MAPT (0.55) | MAPTALDH1A1LMNAPDK2NAMPT | |
| SCHEMBL28738184 | 0.80 | MAPT (0.52) | MAPTALDH1A1LMNAPDK2NAMPT | |
| SCHEMBL25202323 | 0.79 | IP6K1 (0.60) | MAPTALDH1A1LMNAPDK2NAMPT | |
| SCHEMBL7232828 | 0.79 | MAPT (0.55) | MAPTALDH1A1LMNAPDK2NAMPT | |
| SCHEMBL7234678 | 0.78 | MAPT (0.54) | MAPTALDH1A1LMNAPDK2NAMPT | |
| SCHEMBL4429857 | 0.78 | MAPT (0.55) | MAPTALDH1A1LMNAPDK2CKS1B | |
| SCHEMBL5235793 | 0.78 | MAPT (0.55) | MAPTALDH1A1LMNAPDK2CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031707-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |