⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384212 | 0.78 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL27701215 | 0.78 | — | — | |
| SCHEMBL1149443 | 0.75 | — | — | |
| SCHEMBL23809026 | 0.75 | — | — | |
| SCHEMBL13460364 | 0.75 | — | — | |
| SCHEMBL15889041 | 0.75 | — | — | |
| SCHEMBL9885497 | 0.74 | — | — | |
| SCHEMBL1914163 | 0.74 | — | — | |
| SCHEMBL14074643 | 0.74 | — | — | |
| SCHEMBL19937500 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683164-B2 | Nucleic acid derivatives | BIO-RAD LABORATORIES INC. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20090005334-A1 | cyclic moieties which enable the formation of stable hybrids with natural nucleic acids and can therefore be efficiently used in a wide variety of applications and, in particular, in antisense therapy | BIO-RAD LABORATORIES INC. (US) | 2009-01-01 | — | — | US | disclosed |