⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9885497 | 1.00 | — | — | |
| SCHEMBL19121922 | 0.85 | — | — | |
| SCHEMBL11960340 | 0.78 | SIGMAR1 (0.31) | — | |
| SCHEMBL1914163 | 0.77 | — | — | |
| SCHEMBL19937500 | 0.77 | — | — | |
| SCHEMBL27384212 | 0.77 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL14300312 | 0.75 | — | — | |
| SCHEMBL27244058 | 0.75 | — | — | |
| SCHEMBL317945 | 0.75 | — | — | |
| SCHEMBL13460366 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634491-B | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114634491-A | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| EP-3798214-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2021-03-31 | — | — | EP | disclosed |
| CN-101910208-B | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE SRL | 2012-09-19 | — | — | CN | disclosed |
| CN-101910208-A | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE SRL | 2010-12-08 | — | — | CN | disclosed |
| US-7427678-B2 | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method | SIGMA-ALDRICH CO. (US) | 2008-09-23 | — | — | US | disclosed |
| US-7427678-B2 | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method | SIGMA-ALDRICH CO. (US) | 2008-09-23 | — | — | US | disclosed |