Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15382918 | 0.76 | RIPK2 (0.35) | MAPTCYP2C9CYP2C19L3MBTL1MEN1 | |
| SCHEMBL13539409 | 0.76 | TAAR1 (0.40) | MAPTCYP2C9CYP2C19L3MBTL1MEN1 | |
| SCHEMBL13460572 | 0.74 | NPSR1 (0.43) | L3MBTL1MEN1KMT2ANPSR1POLB | |
| SCHEMBL21796409 | 0.72 | SMN1; SMN2 (0.40) | MAPTCYP2C9CYP2C19L3MBTL1MEN1 | |
| SCHEMBL179444 | 0.68 | CYP2C19 (0.44) | MAPTCYP2C9CYP2C19L3MBTL1MEN1 | |
| SCHEMBL11844851 | 0.68 | ALDH1A1 (0.41) | MAPTCYP2C9CYP2C19L3MBTL1MEN1 | |
| SCHEMBL14069077 | 0.68 | NPSR1 (0.38) | L3MBTL1MEN1KMT2ANPSR1POLB | |
| SCHEMBL21501284 | 0.67 | MAPT (0.39) | MAPTCYP2C9CYP2C19L3MBTL1MEN1 | |
| SCHEMBL28311749 | 0.67 | CYP2C9 (0.41) | CYP2C9CYP2C19MEN1KMT2ANPSR1 | |
| SCHEMBL13347572 | 0.67 | MAPT (0.50) | MAPTCYP2C9CYP2C19L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023946-A1 | NOVEL URACIL COMPOUND HAVING NITROGENATED HETEROCYCLIC RING OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2010-03-04 | — | — | WO | disclosed |