Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 9/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460881 | 0.91 | HPGD (0.45) | TP53MAPTHPGDTSHRRECQL | |
| SCHEMBL13461083 | 0.89 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL13460938 | 0.87 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL3418707 | 0.87 | PPARD (0.45) | TP53MAPTHPGDTSHRRECQL | |
| SCHEMBL13460827 | 0.87 | LMNA (0.46) | MAPTTSHRRECQLLMNAPPARD | |
| SCHEMBL13461036 | 0.84 | PPARD (0.46) | MAPTTSHRRECQLLMNAPPARD | |
| SCHEMBL13460747 | 0.83 | LMNA (0.43) | TP53MAPTHPGDTSHRRECQL | |
| SCHEMBL3415779 | 0.82 | PPARD (0.51) | TSHRRECQLLMNAPPARDPPARA | |
| SCHEMBL3413917 | 0.82 | PPARD (0.51) | TSHRRECQLLMNAPPARDPPARA | |
| SCHEMBL13460879 | 0.82 | LMNA (0.47) | TP53MAPTHPGDTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |