Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461109 | 0.92 | ALDH3A1 (0.46) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL30371789 | 0.92 | ALDH3A1 (0.46) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL14023358 | 0.92 | ALDH3A1 (0.46) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL29384404 | 0.92 | ALDH3A1 (0.46) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL13433703 | 0.87 | ALDH3A1 (0.38) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL9237113 | 0.81 | ALDH3A1 (0.48) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL9237119 | 0.81 | ALDH3A1 (0.48) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL9237129 | 0.81 | ALDH3A1 (0.48) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL13433696 | 0.79 | ALDH3A1 (0.40) | ALDH3A1MAPK1MAPTTDP1LMNA | |
| SCHEMBL5564324 | 0.75 | SMN1; SMN2 (0.41) | ALDH3A1MAPK1MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7686852-B2 | Monoazo dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-03-30 | — | — | US | disclosed |
| US-20080028543-A1 | Monoazo Dyes | ARCHROMA IP GMBH (CH) | 2008-02-07 | — | — | US | disclosed |
| EP-1765931-B1 | MONOAZO DYES | CLARIANT FINANCE BVI LTD (VG) | 2007-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080028543-A1 | Monoazo Dyes | IK, CYP3A43, TYR | ALDH3A1 236/4885MAPK1 3255/4885MAPT 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.