Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14492724 | 0.88 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| Obliquin SCHEMBL29534204 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| Obliquin SCHEMBL12062102 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| Obliquin SCHEMBL2255488 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL15671347 | 0.64 | — | — | |
| SCHEMBL18800681 | 0.59 | GAA (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL6802035 | 0.58 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL16904152 | 0.57 | MAOB (0.50) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL29563811 | 0.57 | KMT2A (0.61) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL30954677 | 0.57 | CYP2A6 (0.46) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792623-B1 | Use of extracts and constituents of leontopodium as enhancers of cholinergic function | LEOPOLD FRANZENS UNI INNSBRUCK (AT) | 2010-03-10 | — | — | EP | disclosed |
| WO-2007006492-A1 | USE OF EXTRACTS AND CONSTITUENTS OF LEONTOPODIUM AS ENHANCERS OF CHOLINERGIC FUNCTION | LEOPOLD-FRANZENS-UNIVERSITÄT INNSBRUCK (AT) | 2007-01-18 | — | — | WO | disclosed |