Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969328 | 0.89 | GAA (0.62) | ALOX5TRPA1BACE1GFERGAA | |
| SCHEMBL13464365 | 0.87 | ALOX5 (0.58) | ALOX5GFERGAAALDH1A1PABPC1 | |
| SCHEMBL13464364 | 0.83 | ALOX5 (0.44) | ALOX5TRPA1BACE1GFERGAA | |
| SCHEMBL19463975 | 0.80 | GFER (0.74) | ALOX5TRPA1BACE1GFERGAA | |
| SCHEMBL1968549 | 0.78 | ALOX5 (0.77) | ALOX5BACE1GFERGAAALDH1A1 | |
| SCHEMBL1966034 | 0.78 | ALOX5 (0.63) | ALOX5BACE1GFERGAATP53 | |
| SCHEMBL1967108 | 0.78 | ALOX5 (0.58) | ALOX5TRPA1BACE1GFERGAA | |
| SCHEMBL13464373 | 0.78 | ALOX5 (0.58) | ALOX5TRPA1BACE1GFERGAA | |
| SCHEMBL13464371 | 0.76 | ALOX5 (0.46) | ALOX5BACE1GFERGAAALDH1A1 | |
| SCHEMBL1967393 | 0.76 | ALOX5 (0.74) | ALOX5BACE1GFERGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032195-A1 | IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS | CSIR (ZA) | 2010-03-25 | — | — | WO | disclosed |